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基本説明

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世界ではじめて細胞の全体像を分子レベルから解説したバイブル的教科書の７年ぶりの改訂版。新教材の一例です。エピジェネティックス、幹細胞、RNAi、比較ゲノミクス、最新のガン治療、アポトーシス、細胞周期の制御とＭ相の力学。特徴である一貫した総合的な図解、テーマを明確に伝える見出し、各節ごとの簡潔な要約などは前版のまま。多細胞系に関する第21～25章は付録DVD-ROMにpdfファイル形式で収録。本文内の図表や顕微鏡写真すべてをPowerPoint(JPEG)形式で収録。Media Player入りで、125本以上の動画をすべてナレーション付きで見られる。第1～25章を書籍に収録した「細胞の分子生物学 第５版]参考版(ISBN 978-0-8153-4111-6)もございます。

Full Description

For nearly a quarter century Molecular Biology of the Cell has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter).The hallmark features of Molecular Biology of the Cell have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries. Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features.It is now more portable. Chapters 1-20 are printed and Chapters 21-25, covering multicellular systems, are provided as PDF files on the free Media DVD-ROM which accompanies the book.* And for the first time, Molecular Biology of the Cell now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments, and they will help students review and extend their knowledge derived from reading the textbook. The Media DVD-ROM, which is packaged with every copy of the book, contains PowerPoint (R) presentations with all of the figures, tables and micrographs from the text (available as JPEGs too). Also included is the Media Player, which plays over 125 movies-animations, videos, and molecular models-all with voice-over narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos and animations. The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text as well.By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology.* There is also a reference edition of Molecular Biology of the Cell, Fifth Edition (ISBN 978-0-8153-4111-6) that contains Chapters 1-25 entirely in printed format.

Contents

PART I INTRODUCTION TO THE CELL 1. Cells and Genomes 2. Cell Chemistry and Biosynthesis 3. Proteins 4. DNA, Chromosomes, and Genomes 5. DNA Replication, Repair, and Recombination 6. How Cells Read the Genome: From DNA to Protein 7. Control of Gene Expression PART III METHODS 8. Manipulating Proteins, DNA, and RNA 9. Visualizing Cells 10. Membrane Structure 11. Membrane Transport of Small Molecules and the Electrical Properties of Membranes 12. Intracellular Compartments and Protein Sorting 13. Intracellular Vesicular Traffic 14. Energy Conversion: Mitochondria and Chloroplasts 15. Mechanisms of Cell Communication 16. The Cytoskeleton 17. The Cell Cycle 18. Apoptosis 19. Cell Junctions, Cell Adhesion, and the Extracellular Matrix 20. Cancer Chapters 21-25 available on Media DVD-ROM: 21. Sexual Reproduction: Meiosis, Germ Cells, and Fertilization 22. Development of Multicellular Organisms 23. Specialized Tissues, Stem Cells, and Tissue Renewal 24. Pathogens, Infection, and Innate Immunity 25. The Adaptive Immune System